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In-depth perspectives on psychiatric research, emerging treatments and clinical reasoning.
Explore xanomeline–trospium, the EMERGENT trials, muscarinic mechanisms, safety considerations and the limits of current schizophrenia evidence.
Read articleImage: 3D ball-and-stick model of xanomeline by Chemligand · CC0 1.0. Resized and converted to JPEG/WebP; transparency flattened onto white. Image derivatives retain the source license.
A clinician’s review of semaglutide, HISTORI, COaST and metabolic care in schizophrenia, with practical limitations and safety context.
Read articleImage: Ozempic Semaglutide 0.5mg by Chemist4U · CC BY-SA 2.0. Resized and converted to JPEG/WebP; transparency flattened onto white. Image derivatives retain the source license.
Understand ELEKT-D, KetECT, response versus remission, cognitive effects and the clinical limits of comparing ketamine with ECT.
Read articleImage: Ketamine Vials by Psychonaught · CC0 1.0. Resized and converted to JPEG/WebP; transparency flattened onto white. Image derivatives retain the source license.
Read the 2026 SNT replication alongside earlier TMS trials: targeting, treatment schedules, remission, durability and candidate biomarkers.
Read articleImage: Basic outpatient TMS setup by Technophant · CC BY-SA 4.0. Resized and converted to JPEG/WebP; transparency flattened onto white. Image derivatives retain the source license.
Compare major psilocybin trials, the 2026 EPISODE findings, blinding challenges, adverse events and the limits of current depression evidence.
Read articleImage: Psilocybe cubensis by Alex Abair · CC BY 4.0. Resized and converted to JPEG/WebP; transparency flattened onto white. Image derivatives retain the source license.
Review autoimmune psychosis, encephalitis warning signs, paired antibody testing, diagnostic pitfalls and the role of coordinated specialist assessment.
Read articleImage: Extreme delta brush in anti-NMDAr encephalitis by Tomotaka Mizoguchi, Makoto Hara, Satoshi Hirose and Hideto Nakajima · CC BY 4.0. Resized and converted to JPEG/WebP; transparency flattened onto white. Image derivatives retain the source license.
