Structured reference

Atomoxetine

ADHD · Oral capsule

Reference information · Structured reference
Last content update
2026-10-27
Clinical review
Not independently reviewed
Source jurisdiction
See individual sources
Coverage
Structured reference
What changed in this edition

Clinical essentials #

Reference fieldScope
Formulation / routeOral capsule
Selected adult indicationADHD in adults
MechanismSelective noradrenaline-transporter inhibition.

Indications & formulation #

ADHD in adults. This reference covers the selected formulation; other indications and products need their own evidence.

Dose reference #

Adult educational reference · Oral capsule · United States. The clinician selects treatment after assessment; this page does not calculate or change a prescription.

Start 40 mg/day; after at least three days, target 80 mg/day. If needed after 2–4 additional weeks, maximum 100 mg/day. CYP2D6 modifiers change titration.

Contraindications & important cautions #

Avoid MAOIs, phaeochromocytoma, narrow-angle glaucoma and severe cardiovascular disease. Assess hepatic symptoms and mood changes.

Selected important cautions; consult the full product information for all contraindications and warnings.

Adverse effects #

Appetite, gastrointestinal, sleep and cardiovascular effects require review; follow the selected label’s serious warnings.

Interactions #

CYP2D6 status/modifiers affect exposure. Review cardiovascular disease and contraindicated combinations.

Monitoring #

Monitor function, blood pressure/pulse, weight/appetite and mood-related changes, with age-specific requirements.

Special populations #

Moderate hepatic impairment: half usual dose; severe: one-quarter. Strong CYP2D6 inhibitors/poor metabolism need slower escalation.

Adult scope. Pregnancy, breastfeeding and pediatric use require the exact product’s population-specific guidance and individual assessment.

Discontinuation, restarting & counseling #

The label does not require tapering; reassess function and cardiovascular effects when treatment changes.

Condition-specific prescribing #

Additional indication-specific records retain their own formulation and source context.

Prescribing reference

Atomoxetine

Adult ADHD

Adults · Capsule · Oral · US STRATTERA label, June 2026

Starting dose
40 mg/day.
Titration
Increase to 80 mg/day after at least 3 days; consider 100 mg/day after another 2–4 weeks if response remains suboptimal.
Treatment range / target
Target 80 mg/day; maximum 100 mg/day, once daily or evenly divided morning/late afternoon.
Maximum / limits
100 mg/day.
Trial & duration
Reassess long-term usefulness. Label permits discontinuation without tapering.
Monitoring
Pulse/BP, activation, urinary symptoms and possible hepatic injury.
Population & organ-function adjustments
Strong CYP2D6 inhibitor or poor metabolizer: wait 4 weeks before increasing. Child-Pugh B: use 50% of usual initial/target doses; C: 25%.
Important cautions
Screen for bipolar disorder. Contraindicated with MAOIs, narrow-angle glaucoma, pheochromocytoma and severe cardiovascular disorders. Swallow capsules whole.

Open the condition treatment guide ↗

Brands & products #

Historical catalogue observations. Prices and catalogue presence do not establish current availability or Indian approval.

Reference coverage #

Structured summary of selected adult uses, not an exhaustive monograph. Indian product authorization and local prescribing requirements have not been reconciled.

References · 2
  1. Atomoxetine — Oral capsule — selected prescribing information · United States · Checked 2026-10-27 · Selected formulation: Oral capsule · Supports indications, dose, cautions, adverse effects, interactions, monitoring, special populations and stopping. Source sections: Indications and usage; Dosage and administration; Contraindications; warnings and precautions; Use in specific populations; patient counseling
  2. DailyMed: STRATTERA prescribing information, June 2026 · United States label · Checked 2026-10-26 · Supports: Atomoxetine — Adult ADHD (Capsule)

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