Structured reference

Diazepam

Anxiety and sleep · Oral tablet

Reference information · Structured reference
Last content update
2026-10-27
Clinical review
Not independently reviewed
Source jurisdiction
See individual sources
Coverage
Structured reference
What changed in this edition

Clinical essentials #

Reference fieldScope
Formulation / routeOral tablet
Selected adult indicationAnxiety disorders in adults; withdrawal protocols are separate
MechanismPositive allosteric modulation of GABA-A receptors; active metabolites contribute to prolonged effects.

Indications & formulation #

Anxiety disorders in adults; withdrawal protocols are separate. This reference covers the selected formulation; other indications and products need their own evidence.

Dose reference #

Adult educational reference · Oral tablet · United States. The clinician selects treatment after assessment; this page does not calculate or change a prescription.

Selected label range: 2–10 mg two to four times daily, individualized. This broad range is not a routine target; use the lowest effective dose and review duration.

Contraindications & important cautions #

Avoid severe respiratory/hepatic insufficiency, sleep apnea and myasthenia gravis. Opioid combinations increase respiratory risk.

Selected important cautions; consult the full product information for all contraindications and warnings.

Adverse effects #

Sedation, cognitive/motor impairment, falls, dependence and withdrawal are relevant.

Interactions #

Alcohol, opioids and other depressants increase sedation/respiratory risk; age and hepatic function affect persistence.

Monitoring #

Clarify indication and planned duration, driving/falls risk and a reviewed discontinuation plan. Withdrawal treatment needs a supervised protocol.

Special populations #

Older/debilitated patients: label starts 2–2.5 mg once or twice daily. Long-lived metabolites increase accumulation risk.

Adult scope. Pregnancy, breastfeeding and pediatric use require the exact product’s population-specific guidance and individual assessment.

Discontinuation, restarting & counseling #

Taper gradually; discuss dependence, driving impairment and alcohol avoidance.

Brands & products #

Historical catalogue observations. Prices and catalogue presence do not establish current availability or Indian approval.

Reference coverage #

Structured summary of selected adult uses, not an exhaustive monograph. Indian product authorization and local prescribing requirements have not been reconciled.

References · 1
  1. Diazepam — Oral tablet — selected prescribing information · United States · Checked 2026-10-27 · Selected formulation: Oral tablet · Supports indications, dose, cautions, adverse effects, interactions, monitoring, special populations and stopping. Source sections: Indications and usage; Dosage and administration; Contraindications; warnings and precautions; Use in specific populations; patient counseling

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