Structured reference

Escitalopram

Antidepressants · Oral tablet

Reference information · Structured reference
Last content update
2026-10-27
Clinical review
Not independently reviewed
Source jurisdiction
See individual sources
Coverage
Structured reference
What changed in this edition

Clinical essentials #

Reference fieldScope
Formulation / routeOral tablet
Selected adult indicationAdult depression and generalized anxiety disorder
MechanismSelective serotonin-transporter inhibition by the S-enantiomer of citalopram.

Indications & formulation #

Adult depression and generalized anxiety disorder. This reference covers the selected formulation; other indications and products need their own evidence.

Dose reference #

Adult educational reference · Oral tablet · United States. The clinician selects treatment after assessment; this page does not calculate or change a prescription.

Start 10 mg once daily; if indicated, increase after at least one week to a maximum 20 mg/day.

Contraindications & important cautions #

MAOIs and pimozide are contraindicated. Assess QT-related risk, serotonergic combinations, sodium and bleeding risk.

Selected important cautions; consult the full product information for all contraindications and warnings.

Adverse effects #

Gastrointestinal and sexual effects, activation, hyponatraemia and QT-related concerns in susceptible settings.

Interactions #

Reconcile serotonergic and QT-prolonging medicines and relevant metabolic inhibitors; organ function and formulation matter.

Monitoring #

Assess mood activation, function and tolerability; ECG/electrolyte review is guided by cardiac risk and local product instructions.

Special populations #

Most older adults and patients with hepatic impairment use 10 mg/day. Severe renal impairment lacks an established dose recommendation.

Adult scope. Pregnancy, breastfeeding and pediatric use require the exact product’s population-specific guidance and individual assessment.

Discontinuation, restarting & counseling #

Use a gradual reduction with review of withdrawal symptoms.

Condition-specific prescribing #

Additional indication-specific records retain their own formulation and source context.

Prescribing reference

Escitalopram

Generalised anxiety disorder

Adults · Immediate-release tablets · Oral · United Kingdom product information

Starting dose
10 mg once daily.
Titration
Increase according to response and tolerability within the label range; a fixed increment is not specified in this UK SmPC.
Treatment range / target
10–20 mg/day.
Maximum / limits
20 mg/day for ordinary adults; lower limits apply below.
Trial & duration
Reevaluate benefit and dose regularly; continuation guidance below.
Monitoring
Activation, suicidality, sodium when indicated, bleeding and QT-related vulnerability.
Population & organ-function adjustments
Age >65: start 5 mg/day, maximum 10 mg/day. Mild/moderate hepatic impairment: 5 mg/day for 2 weeks, then up to 10 mg/day. Severe renal/hepatic impairment needs caution.
Important cautions
Avoid MAOIs and known QT prolongation or contraindicated QT-prolonging combinations.

Open the condition treatment guide ↗

Brands & products #

Historical catalogue observations. Prices and catalogue presence do not establish current availability or Indian approval.

Reference coverage #

Structured summary of selected adult uses, not an exhaustive monograph. Indian product authorization and local prescribing requirements have not been reconciled.

References · 2
  1. Escitalopram — Oral tablet — selected prescribing information · United States · Checked 2026-10-27 · Selected formulation: Oral tablet · Supports indications, dose, cautions, adverse effects, interactions, monitoring, special populations and stopping. Source sections: Indications and usage; Dosage and administration; Contraindications; warnings and precautions; Use in specific populations; patient counseling
  2. Escitalopram tablets: SmPC sections 4.2–4.5 · United Kingdom product information · Checked 2026-10-26 · Supports: Escitalopram — Generalised anxiety disorder (Immediate-release tablets)

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