Nicotine

Indications & formulation #

Smoking cessation in adults. This reference covers the selected formulation; other indications and products need their own evidence.

Dose reference #

Adult educational reference · Oral nicotine polacrilex lozenge · United States. The clinician selects treatment after assessment; this page does not calculate or change a prescription.

The label selects 4 mg if the first cigarette is within 30 minutes of waking, otherwise 2 mg. Follow the 12-week schedule and daily limits in the exact product leaflet.

Contraindications & important cautions #

Review recent cardiac events, arrhythmia and symptoms of nicotine excess. Lozenges are not chewed or swallowed whole.

Selected important cautions; consult the full product information for all contraindications and warnings.

Adverse effects #

Mouth irritation, nausea and symptoms of nicotine excess.

Interactions #

Stopping smoke exposure can change clozapine/olanzapine concentrations independently of nicotine replacement.

Monitoring #

Review tobacco use, withdrawal, adverse effects and quit support.

Special populations #

Pregnancy/breastfeeding and unstable cardiovascular illness need clinician review. Keep away from children and pets.

Adult scope. Pregnancy, breastfeeding and pediatric use require the exact product’s population-specific guidance and individual assessment.

Discontinuation, restarting & counseling #

Step down according to the lozenge schedule; other nicotine formulations require different instructions.

Brands & products #

Reference coverage #

Structured summary of selected adult uses, not an exhaustive monograph. Indian product authorization and local prescribing requirements have not been reconciled.